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reenorapyesterday at 5:10 PM3 repliesview on HN

The article acts like ibogaine is a newly discovered drug. This is an old hallucinagenix drug that has helped thousands of people get over ptsd. The only thing holding this back is government bureaucracy and red tape. I’m happy that people will get there chance to benefit from this after decades of stupid government policy.


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b00ty4breakfastyesterday at 11:32 PM

I have a friend who received ibogaine as a treatment, in mexico, for opiate addiction and it is not at all like your average hallucinogenic drug.

for starters, she had to go through cardiac tests before they would even administer the stuff because it can cause serious cardiac symptoms, up to and including death. Somebody in her group was kicked out because they had been using meth the week of the trip (no pun intended). They were telling them that even too much caffeine could increase their risk of cardiac symptoms.

Then the trip itself was like 48 hours and it wasn't a fun trip like acid or mushrooms. The few things she would tell me about were awful, and she still won't talk about most of it almost a decade after the fact.

Some drugs don't need to be caught up in federal approval but ibogaine is absolutely a drug that needs the red tape and all the pomp and circumstance of FDA approval.

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Aurornisyesterday at 10:11 PM

> The only thing holding this back is government bureaucracy and red tape.

Not really true. There have been clinical trials for Ibogaine over the years in the US and abroad. The United States isn’t the only country capable of running trials.

A big blocker for ibogaine is that it’s cardiotoxic. Multiple deaths have occurred within clinical trials for ibogaine. It’s really hard to justify and get approval for additional clinical trials for a drug that has caused deaths even in small trials.

There are analogs of ibogaine being studied, too. These are designed to lack the cardiac properties of ibogaine and would hold much more promise. There’s a real problem of mistrust with “artificial chemicals” that causes this to be ignored while ibogaine gets the attention. I suppose that’s to be expected with politicians driving research.

kreyenborgiyesterday at 9:48 PM

> red tape

Just frame it as "this drug lets you send scarred soldiers right back into the fray for pennies" and see that red tape dissolve

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