alt Hacker News> A major chord is like a blend of two base colors that give rise to a pleasant composite color. Mix the wrong bases and the result is sensibly wrong.
why does a major chord sounds pleasant? and why does a minor chord sounds "sad"? Why does the locrian mode sound so unsettling? is it due to our anatomy or purely cultural?
And even then, in different contexts, a major chord can sound jarring and a minor one satisfying.
That being said the nature/culture duality is often not the right way to frame these issues. It's both, intertwined.