I am not a python dev but have the utmost respect for the ecosystem.
But damn, with all the supply chain attacks now in the news, could they just make a simple way (for non python insiders) to install python apps without fearing to be infected by a vermin with full access to my $HOME ...
There is little that they can do short of running the programs in a VM. Linux distros aren't engineered to consider applications as something different from the user running them. You need a completely different security model to achieve that and the Python runtime isn't tackle that.