You definitely don't want too much realism, for most games - you probably don't want to manage bathroom trips! We just assume it happens "off camera"

But when humanoid enemies behave in plainly stupid ways it's a real immersion-breaker for me. I've been gaming a looooong time, so I'm quite adept at the necessary mental gymnastics to enjoy stuff anyway... but... still... games could be better here. (And by "better" I mean "more fun")