For what's it's worth you can render Jupyter notebooks directly from Typst using the Callisto package. You can then style the notebook content as if it was written in Typst, using show rules, etc:

  #import "@preview/callisto:0.2.5"
  #callisto.render(nb: json("notebook.ipynb"))

though as the sibling comment says Quarto also works great for this, and Typst doesn't do epub (yet?)