> DNA and evolution, even with billions of years to think about it, is really a bit of a beginner when it comes to protein design.
I like how you say evolution is able to think when in reality it's just a mysterious function of variation, selection, and time.
I find it completely daunting to speak of evolutions processes without some anthropomorphism sneaking in, despite being a hardcore atheist.
It's all so complex, and our verbs that more literally describe the billions of nanosecond operations going on in the cells feel inadequate. "When a protein molecule in an appropriate folded shape and orientation happens to be bounced by kinetic energy into the attractive region of a corresponding protease..." versus "The protease grabs the protein and cuts it into..."