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the__alchemisttoday at 3:03 PM1 replyview on HN

Bad-ass! Getting small seqs "oglios" is cheap/fast. (as stated in the article) (IDT or Sigma will courier it to you same or next day, and is ~$10 per) But longer ones is much more expensive!

So... is the "Generative AI" tie in (Mentioned many times, starting at the top of the article) used mainly get funding and press? The core part of this seems to have nothing to do with AI. I am sus this is bullshit marketing based on #1: How many times I've clicked an article, and have AI blasted all over it for sus reasons, and #2: Being able to cheaply and reliably synthesis custom DNA seqs longer than a few hundred/thousand bps is a broadly useful tech for current and future applications.

So: #1: This is really good news. #2: Do better with the hype/bull. It undermines your credibility. So now I start questioning whether this works as well as advertised, and what else they are being shady about.


Replies

biophysboytoday at 4:10 PM

I used to order $10 oligos all the time. The extra length is cool, but I was honestly more impressed by the claims on sequence accuracy in the article. Even a single base pair change can affect the genetics and physics of DNA.

I broadly agree with you on the AI hyping. Data quality and quantity is not high enough in my opinion.