Again, if you disagree with Penrose’s idea, just explain your disagreement.

We can now simulate every aspect of consciousness except for long-term memory consolidation, to the extent that you can't tell if you're talking to a conscious person or a computer. The existence of LLMs means that no quantum woo is necessary to explain consciousness. Our brains just do the same thing by different means.

In short, Penrose's argument is a religious one, not a scientific one.