I remember a big debate "back in the day" about the effects of shutting down your PC at night and the effect on the health of the CPU. The theory at the time was that by shutting down your PC every night, the temperature fluctuations would put more stress on the CPU, shorting its life span. However, the other side said that leaving on your PC all day and night would spend more time running and reduce its life span, so only having it running when you needed it was better. I think a website did a test and found it makes no difference, but I remember it being a big topic around the 2000's (it might have been related to AMD chips at the time running extremely hot)