Interesting. I pasted the article URL into Claude Opus 4.8, along with some questions about uses for cells that couldn't reproduce and Claude thought about it for a while, and then got murdered by the guardrails. I was invited to edit the question and try again; in a different chat. Or use a dumber model.
I suppose I can see why. But at the time I was just curious about the idea of "mule" cells.
Which shows why guardrails on AI are just dumb. What harm could come from answering your question? None.