As someone who worked on logistics optimization algorithms for Amazon, I’ll just say that the one thing Amazon did best was have clueless upper management continuously make poor strategic decisions that continuously nullified all of their improvements from optimization.
What was the root cause of that? (Company consciously prioritized other things than those logistics optimizations? Individual incentives lead to management behavior that was against company's intent? Bad hiring and retention practices for upper management or whomever was informing them?)