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icodestufftoday at 4:46 PM1 replyview on HN

I only know one person who has ever found phenylephrine effective. It's definitely not for me, but they've done single-blinded self-studies (with help) to see if it's a placebo effect, and it's pretty clearly not.

DXM is also not a placebo, although it might be specifically for cough.

I don't especially want the FDA to ban them, but requiring separating out the acetaminophen might not be the worst idea.


Replies

QuercusMaxtoday at 6:15 PM

Phenylephrine only works as a nasal spray. It doesn't do anything when taken orally, because it is broken down in the digestive tract.