The easiest and best way is to rate limit the number of signups from a domain per day. You might still get people trying to bulk signup but as the article states, most large spam operators do not really use those domains anyway. Of course there are plenty of small time scammers to make up for that lack, so to speak.
I personally use burner emails when I want an account somewhere but would prefer not linking all of my personal interests and necessities to the same few email addresses. It just seems smart.
It is frustrating to try to make it clear you are not attempting to bypass authenticity controls, especially when AI can so frustratingly create text posts that can seem realistically 'human'.
Maybe someone will come up with a better way to attempt to add privacy back without ripping it away in the name of attempting to add it.
Though, I mean, that's been the issue since the 1990s: security or privacy, hard to have both, and yet difficult to have either without the other.