yeah. This is one of those things where they used previously collected data, built a model that has validity on modeling validity between simulation and actual brain (encoding model for digital twin), then built a new model using the encoding model that tries to reliably activate particular brain regions. The next obvious step is to validate this back to the original person, but they will need to collect new data, and so likely, will need to get research funding. One step at a time.

The digital twin types of models will become more and more useful, but I don't think we will be at the point where all research will be done entirely within these models.

They can be fun to play with btw: https://www.thevirtualbrain.org/tvb/zwei/ and they don't require a beast of a machine to run.