Once you create an abstraction (like a macro, routine, language) you forfeit the benefits using machine code gives you wherever you use that abstraction, since there could be some bespoke implementation that solves the problem.

That entire point is moot here because the abstraction in this case is a massive ball of crap and it's used everywhere. So you never get the benefit you think you would for using a lower level language. That's why generally LLMs are best with python and even better with a "harness" (domain specific framework and language)