Shinjuku isn't the worst - it's big, but every part of it has its own distinct feel, you never get confused about where you are. I actually think Ikebukuro is the worst - there are too many places where you can rotate 180 degrees, or move up or down a floor, and find yourself looking at an exactly identical scene.

anyone who hasn't been lost in Shinjuku-eki has not been to Shinjuku-eki. Or has been, but it was Golden Week and the place was nearly empty.