Unless those very F-16s shred their way through the AA weapons first, that is. Or follow up once the stealthier, more survivable platforms pave the way.
Iran had a solid AA system - and the level of impunity with which US operated with over Iran should give every country that wants to rely on its AA a pause. US SEAD/DEAD capabilities are fucking scary.
Of all the things that went wrong with Iran: USAF's capability to get in, punch through AA and rain fires from the sky sure wasn't one.