If you're on Windows, MacOS or Linux, a great tool for interactively discovering and deleting large folders and files is dua:

https://github.com/Byron/dua-cli

If you're on MacOS and suspect a lot of space is taken by multiple copies of the same files, use fclones to turn them into APFS clones. (You can also use this on Linux, as ext4 supports hard links, but only if you're sure the duplicates won't diverge.)