Anyone can write out the code for a bad virus. You can go download it from an open repository. It's only through deep interface with the world that the idea for the bad virus turns into an actual bad virus. The fever dreamers will say the LLMs will help you interface with reality to do the bad thing™ which their model let's you do. But you still need thousands to millions of times the effort And once made how do you deliver it in a way that might further your (bad) objectives? Presumably it just makes humans sick. There aren't "targeted" bioweapons, and among humans we are too damn similar for there ever to be. And all of this said, there is almost nothing special about the LLMs' abilities in biology. They only know what we know. They're not being trained autonomously with RL and a robotic wetlab. When that's a thing I'll start to take claims of biology risk more seriously. Right now they have the same logic as the paperclip theory of superintelligence risk. And cynically, it would seem that Anthropic purchased a biotech company and almost immediately decided to lock down biology work with their models.