An important thing to consider is that DEC simply didn't have enough CPU design teams, which is also why Alpha essentially had only one-and-half model in the works throughout its history - and the half came from smashing smallest chipset variant into single chip with the CPU for pretty bad performance (too slow memory, mainly). A low-power Alpha CPU would have to be a from scratch design, even if arguably simple to implement ISA-compatible chip.
StrongARM was developed in partnership with ARM, not starting from zero, applying some of the techniques Digital developed with Alpha to ARM - reputedly creating the idea that ARM could be fast at all
DEC also blew a fortune on the ECL VAX.
"Meanwhile, the engineering team's predictions about the relentless march of CMOS proved true. By 1991, the NVAX was also on the market, offering roughly the same performance for a tiny fraction of the cost and size. At lower performance settings the same design was available in desktop form, outperforming all previous VAX machines. The 9000 managed not only to lose billions of dollars, but also led to the ending of several much more promising designs."
https://en.wikipedia.org/wiki/VAX_9000
DEC also lost Dave Cutler's team over PRISM, which was also a deep cut. Deeper than the ECL disaster? Debatable.
DEC had no hope in the ECL money furnace and the loss of the VMS architect.