Early monochrome devices were largely liquid crystal rather than electrophoretic displays.

The key differences:

- LCD was far lower resolution, often element-based rather than pixel-based displays (though the latter also existed).

- Screen response is far faster, with no ghosting. Electropheretic refreshes tend to take time, particularly at higher-quality or colour settings. Modern LCDs are used in high-performance displays at 60--120 Hz refresh or greater. By comparison, a fast EP/e-ink display might reach a few herz, and many require a substantial fraction, if not more than a second, to fully paint.

- Contrast was low. LCD relies on polarisation filters which greatly reduces foreground/background distinction.

That's not to say that some lessons cannot be learned, but the media do differ.