For me Laguna frequently slightly corrupted text then it would be unable to notice the difference and get stuck making the dumbest conclusions. Thinks like typoed directory or function names. It was a great model other than that, but I ended up just going back to Qwen3.6
Make sure you've got the latest updates - both Poolside and Unsloth updated about a week after release, and that you're running via llama.cpp (I've noticed on the same model and same command line arguments, ik_llama.cpp loses quality for me).
Also just in case you didn't see it, Laguna S 2.1 was having issues on MXPF4 but people on Q4 and Q6 couldn't repeat the problem.