I ran Wayland over Waypipe over WireGuard (Tailscale, in my example), and it worked very well. That over a 1 gbit fiber... shared with whole building/office. In fact, I ran remote AOSP this way.

Now, VNC might actually also work very well over WireGuard or SDN based on WireGuard. Since VNC was designed for LAN, in a time where LAN was the common use case.

For me, low latency is from the past. I always got either wired, Wi-Fi, LTE, or Starlink.