logoalt Hacker News

paimapitoday at 1:44 AM2 repliesview on HN

sample size n=37 of which recruitment only happened in Shanghai without any real control for confounders, only evaluated over a period of two weeks with no longterm follow-ups, the dosage of 40g RS/d is very high (would take about 4-5 large potatoes daily for equivalency or ingesting likely expensive supplement), the crossover compares RS vs CS in the same participants with only a 4 week washout which is a weakness since fermentable fiber persists >4 weeks, also the supplement they used was industry-provided by a starch manufacturer which was weirdly not disclosed

this is a great study if you are an overweight/obese adult without overt metabolic disease, willing and able to consume 90 g/d of starch supplement within a controlled diet, and living in Shanghai with similar baseline fiber intakes endemic to that population. it is extremely not generalizeable to you or even me though I fit more of those characteristics than I care to admit

stay skeptical of small studies like this, friend


Replies

dudisubektitoday at 7:20 AM

> not generalizable

But there's already a general advise on this: eat more fiber.

https://med.stanford.edu/news/all-news/2017/08/hunter-gather...

We're a great ape, our body evolved to process a lot of fiber from fruits and starches. It's the modern fiber-deficient diet that's really weird.

90g/day of fiber is similar to the Hadza tribe diet, where they can consume 100-150g of fiber per day.

show 1 reply
lluisantonitoday at 5:25 AM

Also, the authors claim the starch "inhibited lipid absorption." They do not argue why they used surrogate blood biomarkers instead of residual energy output in fecal samples (which is a better measurement).

sample size is 37, number of authors 29