I am entirely unconvinced that a 5% difference in fructose vs. glucose is a meaningful difference.
They carry the same health risks if eaten in the same amounts. The only thing that corn syrup could be blamed for here is being too cheap so it shows up in greater quantity and in more products than cane sugar might otherwise.
HFCS is just one of those fashionable things to be "concerned" about so we can all miss the forest through the trees.
The difference is in the chemical bond.