I'd caution: GLPs reduce your appetite, but they do not fix your diet.

I am not anti-GLP, someone who believes using GLP drugs is cheating and people should achieve that with blood, tears, and sweat. I see it as a "tool" in the arsenal. I've no use for GLP as I've no problem sustaining deficits as large as 600-700kcal for long. But I've met people who can't do this, so for them GLP is a valid choice, but I'd recommend they pair it with proper dieting and lifestyle changes.

You want to eat good stuff and avoid stuff not good for you; blanket reducing appetite may result in loss of both good and bad.

Here's what GLP users say about the macrocodex method: https://www.reddit.com/r/tirzepatidecompound/comments/1omfgx...

The guide linked in the above post is macrocodex's prototype method, which was later formalized into an app.

I don't want to make strong claims on this, but using GLPs may increase the risk of developing gallbladder stones, as GLPs make it very easy to eat far less than necessary.

A proper macro and calorie balanced diet can give you better results with a smaller GLP dose.

Use GLPs if your actual problem is staying on a "sustainable deficit." Many people who use macrocodex report they do not feel hungry when on such a small deficit, but there are a few who are hungry even at a deficit as low as 300 kcal; for them, GLPs are more suitable, but not a replacement for proper dieting and lifestyle changes.