alt Hacker NewsNot 100%
In certain cases you can use information asymmetry to your advantage. You know something they don't. A good example is any market dependent on public opinion surveys (eg political polling). That data can be hard to find. If you can find it faster than everybody else then you win more often. There is still some chance involved but it's more like poker than blackjack (not a great analogy but you get my drift).
People did this in sports gambling since forever. Professional gamblers would cultivate a source (like a coach) to get inside information to get a leg up. That said - you are still placing a bet based on the best information you have. It's gambling, or else, what other word is for it? Investing?