mRNA is a general technique for targeted cancer therapy. It's the message RNA containing the instructions from a gene to create a specific protein. It's much easier to work with, reprogrammed, manufactured, and delivered. There're a number of approaches to use mRNA against cancer cells. One is using cancer related antigens, similar to the vaccine approach. mRNA is programmed to generate the antigen proteins in the body, which are attached to the cancer cells. The body's T-cells can then attack the tagged cancer cells.

The problem now is finding the correct antigens targeting the cancer cell type. Cancer cells are similar to health cells. You don't want to program a mRNA to generate antigen proteins that target health cells, which causes autoimmune problems.