alt Hacker NewsSyndicate on MS-DOS is the only game I know of to look good with 16 colors on VGA 640x480. The other one would be Gods by Bitmap Brothers also 16 colors but on 320x200 resolution. Great examples of limitations driving amazing outcomes.
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I feel like the limitations are the reason some/most of those games were so good.
Imagine a modern Syndicate remake... it would "have to" be MMO, it would "have to" have character development, as in the stats would go up. It would "have to" be "rogue-like" (ie procedural level generation, no story.)
It's a non-starter. No studio would accept the idea of the game as it is, since the graphics required to be "modern" would need an amount of work that wouldn't mix with the length of the gameplay of the original.
Bitmap brothers are also responsible for one of the most underrated RTS games imo: "Z"
All of the big Bullfrog games were unique and for some reason never spawned imitators. Populous, Magic Carpet, Theme Park/Hospital, Dungeon Keeper alongside Syndicate