Risk of transmission of amyloid β pathology via transfused blood products

I don’t believe the plaques have been shown to be prion based, but who knows what the transmission mechanism might be.

More relevantly, the etiology is still a mystery, and nobody knows if the amyloid β is a defense, cause, mechanism, or harmless side effect of Alzheimer’s. Drugs attacking plaque have not made a difference on the disease in clinical trials. In fact the plaque theory seems to have been supported by fraud (causing a president of Stanford to be ejected) and distracted research for years.

People are working on other causes, most of which lately has focused on the tau protein.

> The recent recognition of iatrogenic amyloid β cerebral amyloid angiopathy (CAA) and Alzheimer's disease, caused by inadvertent seeding of amyloid β pathology following historical medical procedures

That doesn't explain why shingles vaccinations are (somewhat) protective against Alzheimer's.

Would you say that modern medical science is truth-motivated or profit-motivated? 50-50? 60-40?

We should be cloning monoclonal antigen free humans and harvesting blood from factories.

All of medical science still imagines a world where humans are in "God's shape", denying the fact that we are machines made of systems of smaller machines.

We could clone headless humans and have factories full of them. Transplants could cure all but brain cancer. Reverse aging too.

Every time I meet a postdoc biologist and hear them drone on about the limits of detection, I'm furious we are overlooking the obvious answer to everything. The mechanization of the human body as a plant and lab.

It's just going to take someone bold enough to do it, because people look at this as a horror. Like the first medical inquiry into cadavers being an affront to God.

It would fix everything and propel the biological sciences hundreds of years into the future.

We are dumb superstitious apes.