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brandonbyesterday at 9:31 AM4 repliesview on HN

Agreed that we can't do as much as we'd like. There are some general health things that are believed to prevent cognitive decline, such as managing cholesterol, HbA1c, blood pressure, sleep apnea, etc. One phrase I've heard is that cholesterol at age 50 predicts cognitive health at age 70.

But hopefully we'll start to have more options and wider approvals for things like anti-amyloid drugs.


Replies

computerdorkyesterday at 9:40 PM

Hi there. Actually, Leqembi is a 1st gen Alzheimer’s drugs and targets amyloid plaques. But, like other responses, amyloids doesn’t seem to be hugely responsible for Alzheimers, which is why targeting things like tau proteins is being explored.

xatttyesterday at 12:07 PM

> anti-amyloid drugs

Isn’t the viewpoint in the last decade that amyloid plaques are likely a finding rather than the underlying cause of Alzheimer’s Disease?

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pokot0yesterday at 10:14 AM

if cholesterol predicted future cognitive health we wouldn’t need dedicated tests, do we?

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asturayesterday at 12:38 PM

You can do all that without an expensive blood test.