alt Hacker NewsVenlafaxine has a small half-life so that might be why if you miss a dose by a few hours you'd get withdrawal symptoms. Drugs is leaving fast you body and so concentration is quickly decreasing. Apparently there's a extended-release, don't know if it's already what you have but maybe you could ask to try another SNRIs that has a longer half-life.
Yep I’m on XR, I’ve tried taking half my dose twice daily instead, which did smooth out the effects a bit but also made me much more likely to miss a dose. Not really any other solution other than tapering afaict.