FWIW findings about adverse events vary considerably:

> The proportion of patients reporting adverse events ranged from 16% to 98% (median 80%) under SSRI treatment and from 17% to 94% (median 70%) under placebo [1]

So the answer IMO depends on whether we can attribute adverse effects to treatment, which is difficult to disentangle from adverse effects of disease

I’m open to being shown more certainty if available from the literature but meta-analyses are high-strength evidence

[1] https://www.cambridge.org/core/journals/the-british-journal-...

What's wild about that? What does the science say?

I've tried a variety and I can't say whether I've experienced side effects. That's just an anecdote but that's the thing with this discussion, that's all you will get. If people don't suffer side effects, they're not likley to get on HN and post about them, etc.

The bigger issue is the person dealing with these issues is taking them because they are not well-off. If you deal with reduced desire, for example, is that a side effect of the medication or is that a side effect of being depressed.

I think your "wild" is a little flippant or telling because it just points back to anecdotes.