Of course you can.

Random non technical executive goes to a login page, and a popup happens on an external device like a phone or keychain dongle, watch, or any secondary display that asks "Allow aws.amazon.com root access to open browser tab on laptop xyz?" and if the page you are on right now says "doordash.com" and you did not ask to decrypt aws root credentials, then you say "nope, that does not seem right" and the attack is stopped cold.

The first mistake was letting non technical executive have aws root access in the first place, but the password manager only releasing a single credential at a time with a physical button press on a trusted screen can still be a last line of defense for our most sensitive credentials.

Being user friendly and being able to have any defense at all against malware are not mutually exclusive.