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culiyesterday at 9:15 PM3 repliesview on HN

As with many psychoactive plants and foods, the adaptation here isn't so much a genetic/physiological tolerance as it is an often in-depth body of knowledge/practices for how to utilize the drug/medicine safely. Look at the notorious Datura for example which can cause you to go into a delirious state for over 2 days. The amount of preparation, processing, and knowledge that goes into administering it safely is lost on modern day kids who simply read an Erowid experience about a powerful psychoactive plant that likely grows locally.


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ux266478yesterday at 10:22 PM

Most kids that are ingesting the devil's trumpet are doing so explicitly because they're chasing after the anticholinergic toxidrome and the badge of honor. "Safe" doses of nightshades like datura and belladonna dilate your pupils and make you sleepy. That's not what they're interested in the plant for.

rootsudotoday at 4:06 AM

Tbf for me, erowid introduced the idea and taught me how to safely consume it.

Then said friends I introduced it to decided to freewheel it once and did end up in a state for 2 days.

So I guess information is power or something.

Loughlayesterday at 9:42 PM

Datura is fucking dangerous. Deliriants are no joke in general. That one in particular is really dangerous because it grows absolutely anywhere and is very easy to identify.

Source; chemistry was my favorite class in high school and college because it helped me understand how to extract what I wanted from plants like jimsonweed and Mimosa trees.

Also no one should do that.

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