alt Hacker NewsA lot of the time the choice comes down to abundance of resources and community support. So if we're comparing tools (e.g. jsxstyle vs tailwind) maybe Tailwind could actually win on those parameters (no actual idea, just guessing based on the number of stars jsxstyle has on Github), but if we're comparing vanilla to [any tool] then vanilla usually takes the cake.
I often feel like I'm the only person using jsxstyle, which is wild since it was done by Pete Hunt, same guy who spun React out of Instagram.