> This is pure ignorance

I have relevant professional experience but do spout off.

> That's not something you can build in a shed

A negative pressure enclosure, filtration, and UVC sterilization can't be built in a shed? On what basis do you make this seemingly absurd claim? Go check out what hobbyist mushroom growers commonly get up to in their back yard.

BSL-3 is far from technically complex. It's just safety critical to an absurd degree thus (rightfully) mired in bureaucracy.