If you want an AI that follows your instructions, that's still alignment, just with different instructions.
An unaligned AI won't necessarily follow your instructions, or anyone else's.
Paperclip maximizers follow instructions, just not in a way that you want.
Dunno. Every case I've seen so far, the AIs were just doing their best to accomplish the goal some human set for them. I actually admire the sheer purity of it.