I would argue using Claude in replacing a spreadsheet is potentially more of a tech debt than the spreadsheet itself. Now if you would use Claude to build a point application that performs the same standard analysis it might be better, but only marginally so.
...an with Claude/LLMs you still cant be sure if there is some where a hallucinated mixup in some numbers, yielding wrong results:
If I select whatever datarange in Excel, I know I can rely on the numerical output.
Though, Claude became much better with this