Firefox with sponsorblock installed and ublock origin?

Freetube is pretty great, also you can import your newpipe subs. Http://Freetubeapp.io

Shameless promotion here but I think https://channelsurfer.tv is a good experience.

Brave browser.

I'm not sure about transferring subscriptions between Pipe and Brave...?

Grayjay I'd say. Also works great on Android.

It's not that well known, but mpv supports playing youtube videos. I think you need yt-dlp installed.

Freetube if it's still working? I haven't tried it in a while.

Chrome with sponsorblock and ublock origin lite