Eh, sorta. Fifty years ago was 1976 (I know, right?!). The 747 debuted in 1970 with high bypass engines. The A320 came out in 1988 with fly-by-wire and all Airbus aircraft since have been the same.

The biggest change from then to now is probably the amount of solid state electronics onboard. That's ridden roughly the same curve as other industrial and commercial applications.