Where do you draw the line and say that the arithmetic regarding suffering lab animals versus suffering humans does or doesn't add up?
The answer is far from obvious for many people and so obvious as to not need discussion for others. But the proportions of the population that fall into each group varies over time, from place to place, etc., as does the fraction of each group deciding for or against animal experimentation.
Odd that in all the comments I have read so far no on has yet mentioned the many apparently faceless octopods, chickens, turkey, lambs, pigs, goats, and cows many of us consume each week and how they ended up in our mouths; the same mouths now discussing mouse welfare. Yes, odd.