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bahmboo • today at 1:18 AM • 2 replies • view on HN

Interesting. In TFA they don't focus on that, they say:

"Developing a drug involves many varied tasks: doing early research to identify a target for a drug and the right type of drug to engage it, designing a molecule with the right properties, optimizing it to be manufactured reliably at scale, drafting the regulatory filings needed to run clinical trials, designing and administering those trials, and much more.

Our strategy to realize AI’s medical benefits is based on having AI increasingly involved in all of these tasks."


Replies

timr • today at 4:56 AM

That's all true, but they don't mention the relative costs of those different tasks, or how AI helps them.

Optimizing molecular properties of a lead is important, but ultimately not a huge source of costs. In any case, LLMs probably have as much chance of predicting outcomes as anyone else (i.e. very small).

Manufacturing is somewhat expensive, but most of the cost sits in actually creating a production process, which is not a thing LLMs can do.

Clinical trials are where most of the costs lie, but unless you can create a magical classifier that can tell me if my drug will make it past phase 3, you're not significantly bending the cost curve.

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mrtesthah • today at 3:06 AM

Administering phase 3 drug trials is the most expensive part of the process by far. They conveniently put that at the end.

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