I've attempted to get researchers to use lossless H.264 to encode CT scans. They typically use directories full of tiffs. Even with intra-slice compression (i.e. tiff compression) they are pretty huge. But H.264 will let you recover the original images to the individual bit, and save a huge amount of space thanks to inter-slice similarities.

They are still using directories of tiff, though.

Lots of hardware requires specifically h.264 as a transit; many of the MPEG standards are built around it. So this lets you get MPEG-PS, or lossless BDs, or some hardware/specialized software decoders for machines that otherwise couldn’t keep up (like set top boxes).

prores is not lossless. It's also an intraframe codec so compression is not great.