This is much longer (22h) than starship ever spent coasting, right? If it doesn’t make it back I’d expect problems with boil off.
That’s probably part of the point, to get real data on boil off and how they will need to spec their cooling system for the lunar and mars missions.
They have several points where they can take an earlier backup option for de-orbiting. So they'll have the teams check things constantly, and only wait if they're confident that things look good for their de-orbit burn.