It could be absolutely exasperating, even in 2010 (especially then since browser support for touch events was still shaking out).

The problem is that even without a framework, you didn’t have a blank slate (which would have been better). You had a moving target of blank slates, you had platform differences, you had drag vs touch-drag, entrenched older browsers and the simple frustration of testing on an array of real devices, all sorts.

Now, if you were talking about 2015, then it starts to get a bit flatter.