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__MatrixMan__ • today at 3:45 AM • 2 replies • view on HN

The device used to make oligonucleotides is pretty much an inkjet printer, from there it's cleverly applied enzymes to assemble the full strand. If you've got the skills and determination to get the synthetic DNA into a functioning cell, I don't think limiting access to synthetic DNA in the first place is going to stop you.


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car • today at 4:13 AM

The device used to make oligonucleotides is pretty much an inkjet printer, from there it's cleverly applied enzymes to assemble the full strand.

Usually the synthesis of oligonuclotides is done with phosphoramidite chemistry [0]. So tell us more about those enzymes to make DNA molecules from scratch.

[0] https://www.twistbioscience.com/blog/science/simple-guide-ph...

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