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torcete • today at 11:06 AM • 1 reply • view on HN

When I read about self-replicating RNA I always think about the equivalent in the protein world, the prions. One can make many parallelisms with these scary proteins, responsible of the Creutzfeldt-Jakob disease.

Of course, the are too many limitations for evolving into some more complex, but they can self-replicate and they can infect other organisms. If we could give them an oceanic soup of PrPC and enough time, who knows?


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anonymous_sorry • today at 11:48 AM

Prion "replication" seems rather different from self-replicating RNA.

Isn't the building block that a prion requires to create a copy of itself essentially a chemically almost-identical protein that is just folded differently?

How about an alternative analogy of the prion folding pattern spreading through chemically-similar molecules like a meme through a population of similarly conditioned brains?

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