w/r/t the HIV thing - there are HIV immune populations in Scandinavia who have a natural mutation affecting CCR5, so there is at least some reason to believe it’s safe to edit or knock out.
https://pubmed.ncbi.nlm.nih.gov/14636691/
That is interesting.
Do Scandinavians have compensatory mutations on other proteins, which allows them to have a mutant CCR5?
Presumably CCR5 exists for reason other than attracting HIV.
That is interesting.
Do Scandinavians have compensatory mutations on other proteins, which allows them to have a mutant CCR5?
Presumably CCR5 exists for reason other than attracting HIV.