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arrosenbergtoday at 4:05 AM1 replyview on HN

w/r/t the HIV thing - there are HIV immune populations in Scandinavia who have a natural mutation affecting CCR5, so there is at least some reason to believe it’s safe to edit or knock out.

https://pubmed.ncbi.nlm.nih.gov/14636691/


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pazimzadehtoday at 4:58 AM

That is interesting.

Do Scandinavians have compensatory mutations on other proteins, which allows them to have a mutant CCR5?

Presumably CCR5 exists for reason other than attracting HIV.

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