I stopped taking esomeprazole after being on it for 4 years, and frequently had to supplement with famotidine and tums anyway.

I had an infection and was prescribed antibiotics, and needed to pause the esomeprazole. I asked gemini about it and it suggested I take two probiotics while on the antibiotics, Saccharomyces boulardii and Lactobacillus rhamnosus GG. I noticed after a few days that I wasn't getting heartburn, and started putting the pieces together.

After the antibiotics ended, with still no heartburn, it recommend I add rhamnosus gg to the mix. So now I take all three daily and rarely get heartburn. It's been quiet a shock

Im not saying to live this way, but a super restrictive test diet may open your eyes to some thing and then you can add back.

I even once read that someone noticed an issue they tried to clear up for years with doctors went away on day 3 of a water fast. No, he wasn't going to fast forever. But he was shocked the first relief he ever had was that day. From there he solved his problem once his eyes were opened a bit.

I'd personally try all ground beef for a week or two. It won't kill you. Is it ideal? Probably not. But you will not have any problems from that short trial. Then add things slowly until you have a whole good diet you like.

It may not work for you but I had years of chronic heartburn. While sick with covid in 2020, I stopped consuming coffee and alcohol. It took a few months and for the long covid symptoms to subside, and then no more heartburn. At all. I felt really dumb that I never connected it to coffee before. I didn’t experience direct symptoms from coffee and I didn’t consume an excess amount. But it definitely was the cause.

not the commenter but I bake my own soda bread and found that i was getting heartburn from the salt that was in the recipe. once i eliminated that i could eat as much as i wanted. I also cannot eat salt preserved potato chips on consecutive days.

It might not be gluten (protein) that is affecting you, but the fructans (carbohydrates) that are found in wheat, rye, and barely which are high in FODMAPs.

Look into low-FODMAP diets if you haven't already.

My "chronic" acid reflux disappeared at USMC boot camp so...exercise, no snacking, no alcohol, and rigid sleep schedule?

There are many resources online on which foods trigger gerd and reflux. Also, try the whole30 anti inflammation diet, and don't eat at least 2, preferably 4h before bed.